INDENA’S NEWS @IN-VITALITY 2024:HIGH-QUALITY NATURAL SOLUTIONS TO MAINTAIN METABOLIC BALANCEAND A NEW APPROACH TO BRAIN HEALTH

Milan, 20th November 2024 – A balanced metabolism and a good brain health are two of today’s most
important health needs. Nature can offer effective support through high-quality botanical ingredients, like
those Indena is showcasing at in-Vitality 2024.
To share insights and updates on such important topics, the leading Italian nutraceutical company waits for
its guests on 20th and 21st November, at Milano MiCo, booth 239.
“We are delighted to participate this year too in In-Vitality. Indena wouldn’t miss one of Italy’s most important
events for staying up-to-date in the health and wellbeing sector – says Francesca de Rensis, Marketing
Director at Indena -. Researching, scientifically validating, and producing the highest quality botanical
ingredients has been our commitment for over a century and it continues to be our mission, dedicated to
people’s most important health needs, such as metabolic balance and mental and emotional wellbeing, the
themes we are focusing on for In-Vitality 2024”.
INDENA’S BOTANICALS FOR METABOLIC BALANCE
A balanced metabolism is essential for global health, especially in fighting complex conditions like metabolic
syndrome. Indena’s botanical extracts play a key role in addressing this need: among the company’s main
products for metabolic balance are its artichoke derivatives, specifically Bilear®, and its standardized
bergamot extract, Vazguard®.
Main components of artichoke leaves have reported biological activities like cholesterol lowering and
modulating inflammatory parameters and biomarkers. Genus Cynara has different species with different
geographical distribution, and Indena can successfully support the supply chain of both the most important
cultivars: Cynara scolymus and Cynara cardunculus. One of the most important products Indena developed
from artichoke is Bilear®, a standardized aqueous phenolic extract from the leaves of globe artichoke with
minimal content of cynaropycrin. Scientific evidences show that Bilear® significantly ameliorates dyspepsia
symptoms, reduces symptoms of irritable bowel syndrome and really improves plasma lipid profile, therefore
improving the quality of life overall.
Indena’s Vazguard®, a standardized bergamot extract formulated with Indena Phytosome™ for enhanced
bioabsorption, also provides significant support for metabolic balance, maintaining the same phytochemical
profile as natural bergamot juice. It effectively addresses metabolic syndrome challenges by promoting
healthy management of visceral abdominal tissue, blood sugar, cholesterol, and triglyceride levels.
Scientifically validated, Vazguard® is a natural solution for optimal well-being by comprehensively supporting
various metabolic health parameters. Last but not least, it has a unique and controlled supply chain from
Calabria (Italy).
“Our portfolio offers many different solutions to help keeping metabolism balanced, starting from Vazguard®,
our bergamot formulated with Indena Phytosome™, and our artichoke derivatives such as Bilear® – says
Martino Meneghin, Area Manager Italy&Greece at Indena -. For brain health Indena has the “golden four”
ingredients, scientifically proven to ameliorate cognitive function and support emotional health: Virtiva® Plus
(ginkgo biloba with Phosphatidylserine), Enovita® (grape seed extract), Mirtoselect® (bilberry extract), and
Relissa® (melissa Indena Phytosome™). Many of these extracts are formulated with Indena Phytosome™,
our multi-talented technology platform, a stable and solid dispersion of botanicals or natural compounds into
a 100% food-grade matrix based on lecithin, leveraging synergy to unlock their full power for health”.
THE NEED OF BRAIN & EMOTIONAL WELL-BEING AND INDENA’S NATURAL SOLUTIONS
Maintaining optimal brain health is a growing concern across all ages. Young people struggle with constant
distractions, adults manage demanding lives, and seniors face age-related cognitive decline. These factors
can significantly affect emotional well-being and mental balance. However, nature provides a rich source of
botanicals to enhance mental acuity and emotional well-being naturally. By combining scientific rigor with the
highest quality standards, Indena has developed premium, scientifically-proven ingredients to improve
cognitive function and support emotional health.
Indena’s products designed to support brain and emotional health are four powerful extracts: Virtiva® Plus,
Enovita®, Mirtoselect® and Relissa®.
Virtiva® Plus combines standardized ginkgo biloba extract with phosphatidylserine, a key brain
phospholipid, to synergistically enhance memory, learning, vocabulary, and concentration. Enovita®, an
innovative grape seed extract, offers dual benefits for cardiovascular and mental health. It has been shown
to improve both endothelial function and mood regulation, effectively combating stress. Mirtoselect®, a
unique bilberry extract standardized to contain over 36% anthocyanins, boasts extensive scientific validation
in human studies for its positive impact on vascular and eye health.
Building on the proven benefits of these extracts for microcirculation, vascular health, and eye health, Indena
is currently conducting new research to explore their potential cognitive benefits, particularly in areas like
memory, concentration, and visual acuity.
Brain health and emotional well-being are intrinsically linked, and Indena recognizes this connection with its
innovative product, Relissa®. This health food ingredient maximizes the power of Melissa officinalis,
commonly known as lemon balm, and offers better biological performances through Indena Phytosome™
technology platform, while still fully respecting its natural profile Relissa® stands out as a standardized,
reliable, and melatonin-free solution for promoting restful sleep and combating daily stress. Unlike traditional
lemon balm supplements, Relissa® provides precise quantification and formulation of its key active
compounds, ensuring consistent efficacy. Recent clinical studies demonstrate Relissa®’s ability to
significantly improve sleep quality, mood, emotional balance, mental health, and overall quality of life.
ATTEND INDENA’S PRESENTATIONS
Dr. Renato Iguera – Corporate Botanical Consultant for Indena and President of Assoerbe –
The quality of botanicals in dietary supplements.
The presentation will be focused on the key challenges related to the quality of botanicals in dietary
supplements, emphasizing the importance of traceability and continuous monitoring throughout the entire
supply chain, from the raw plant materials and the concentration to the final product.
NOVEMBER 20TH, 11:15 AM, ARENA
Dr. Elisabetta Frattini, Head of Scientific Communication & LCM at Indena – Boost your brain and
mental health with the help of nature.
NOVEMBER 21ST, 12:10 AM, TEATRO 2
VISIT INDENA AT IN-VITALITY 2024: BOOTH 239
20-21 November 2024 – MiCo, Milan

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